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研究發現:多吃西蘭花有助于減緩乳癌細胞生長(中英雙語)

青島希尼爾翻譯公司(www.eacrwc.tw)整理發布2016-02-17

希尼爾翻譯公司(www.eacrwc.tw)2016年2月17日了解到:SAN FRANCISCO, Feb. 13 (Xinhua)——A compound found in broccoli and other cruciferous vegetables has been found to slow the growth of breast cancer cells, especially at early stages.
  新華社舊金山2月13日電——研究發現,含有西蘭花及其它十字花科蔬菜的混合制劑,有助于減緩乳腺癌細胞的生長,尤其是在發病早期。
  While sulforaphane has long shown evidence of value in cancer prevention, researchers at Oregon State University (OSU) and the Oregon Health & Science University suggested in a new study that it may play a role in slowing cancer growth as well.
  花椰菜和其他十字花科蔬菜含有的蘿卜硫素長期以來就被證明具有防癌價值,而據俄勒岡州立大學及俄勒岡衛生與科學大學聯合進行的新研究顯示,蘿卜硫素還能減緩癌細胞的擴散。
  The findings were the result of the first clinical studies to look at the effect of sulforaphane on breast tissues of women diagnosed with breast cancer.
  這項研究測試蘿卜硫素對患有乳腺癌女性的乳腺組織的效果,而該新發現正是第一次臨床應用后所得出的結論。
  Emily Ho, a professor at the OSU College of Public Health and Human Sciences, said "our original goal was to determine if sulforaphane supplements would be well tolerated and might alter some of the epigenetic mechanisms involved in cancer."
  俄勒岡州立大學公共衛生和人文科學學院的教授何艾米麗說:“我們最初的目標是想確認蘿卜硫素補充劑是否有很好的耐受性,并看它是否能改變與癌癥相關的表觀遺傳機制。”
  In a double-blind, randomized, placebo-controlled trial, 54 women with abnormal mammograms were given either a placebo or supplements that provided sulforaphane. The amount of sulforaphane they received would equate to about one cup of broccoli sprouts per day, if eaten as a food.
  在一個雙盲的、隨機的、安慰劑對照試驗中,科研人員向54名乳房X光出現異常的婦女分發含有蘿卜硫素的安慰劑或營養片劑,每一片安慰劑或營養片劑所含的蘿卜硫素成分相等于一天一杯的花椰菜芽分量。
  "We were surprised to see a decrease in markers of cell growth, which means these compounds may help slow cancer cell growth," said Ho. "This is very encouraging. Dietary approaches have traditionally been thought to be limited to cancer prevention, but this demonstrated it could help slow the growth of existing tumors."
  何艾米莉教授說:“讓我們感到意外的是,癌細胞標記明顯在下降,這意味著這些成分有助于減緩癌細胞增長。這個結果非常鼓舞人心。一直以來,人們以為飲食療法僅限于預防癌癥,但這項研究證明,它也能減緩已有的癌細胞的擴散。”
  Previous studies have found that women with a high intake of cruciferous vegetables, such as broccoli, cauliflower, cabbage or kale, have a decreased risk of breast cancer. In particular, sulforaphane appears to inhibit histone deacetylases, or HDACs, which in turn enhances the expression of tumor suppressor genes that are often silenced in cancer cells.
  先前的研究顯示,女性多食用西蘭花、菜花、卷心菜、羽衣甘藍等十字花科蔬菜,可以降低患乳腺癌的風險。特別是,蘿卜硫素可以抑制組蛋白脫乙酰酶或HDACs,這反過來又能促進原本在癌細胞內的不活潑的腫瘤抑制基因的增長。
  In the new study published in the journal Cancer Prevention Research, the intake of sulforaphane did reduce HDAC activity, as well as cancer cell growth.
  這項刊登在《預防癌癥研究》刊物中的研究結果也指出,女性攝取蘿卜硫素后,不但癌細胞增長減緩,就連組蛋白脫乙酰酶活性也降低。
  As co-author of the study, Ho said it is possible that sulforaphane may be added to traditional approaches to cancer therapy, whether to prevent cancer, slow its progression, treat it or stop its recurrence.
  作為該研究的合著人,何艾米莉教授表示,蘿卜硫素可以加入到傳統治療癌癥的方案中,無論是預防癌癥、延緩癌細胞擴散、治療癌癥或是阻止其復發。
  Researchers said additional studies are needed to evaluate dose responses, work with larger populations, and examine the responses of other relevant molecular targets to either foods or supplements containing sulforaphane.
  工作人員表示,尚需進行大量的研究來評估劑量反應及更廣泛的人群的適應性,并確認其他相關的分子——無論是食物或是補充劑——的反饋效果。
  來源:新華網

 

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